bit.bio
bit.bio’s mission is to apply the principles of data science to biology to code cells for the wellbeing of humanity. Its proprietary technology, opti-ox, enables highly efficient and consistent reprogramming of human cells for use in research, drug discovery, and cell therapy. This scalable platform for the production of human cells is also the basis for a new generation of cell and tissue therapies.
bit.bio is an award-winning human synthetic biology enterprise. bit.bio's mission is to code cells to advance the wellbeing of humanity. To do so, we apply the principles of computation to biology.
Our current focus is to develop a scalable technology platform capable of producing consistent batches of every human cell. This has the potential to unlock a new generation of medicine: it will enable research and drug discovery to move on from inappropriate models and work with the cells that actually are affected by human disease. A scalable platform of consistent cells will also be the basis for a new generation of cell and tissue therapies.
To achieve our goals, we have assembled a team of pioneers in stem cells, cellular reprogramming, mathematical modelling, and cell therapy.
Collaboration is at the heart of bit.bio. We are empirical, highly ambitious and driven by a common purpose. For more information visit www.bit.bio
Every cell, every patient, everywhere.
Products and services
"A code script... must form the kernel of biological theory" - Sydney Brenner
bit.bio is based on a new paradigm in biology. We look at a cell as if it were a computer. In this paradigm, the nucleus is the hard drive and stores genes in its DNA. Genes interact with each other to create programs called gene regulatory networks (GRNs); together these programs form LifeOSTM, the Operating System of LifeTM. At any particular moment in time, only a subset of these programs are active. These determine the function and identity of a cell.
The activity of genes and their related GRNs is controlled by transcription factors (TFs). These are the ‘code words’ of LifeOS. A unique combination of 1-6 TFs defines the identity of every cell.
Our precision cell programming technology opti-oxTM enables deterministic activation of TF codes to program new cell identities. opti-ox reprogramming overcomes the ultimate barriers of cell manufacturing and enables precise, rapid (one order of magnitude faster) and scalable generation of pure human cell types.
